3rd Party Lab Tested
Clinically studied doses, in exactly the right combination, for an effective and safe amount with every dose.
The power of a scientifically validated methyl donor
TMG (Trimethylglycine), also called betaine, is an amino acid derivative that serves as a methyl donor, meaning it transfers methyl groups, enabling methylation, a key biochemical process that sustains life.
Found in select foods such as beets, spinach, and quinoa, TMG plays a vital role in supporting cardiovascular function, cognitive health, cellular metabolism, and healthy aging.
As we age, the biological demand on methylation pathways increases, making reliable access to methyl donors increasingly important.
GenuinePurity® Liposomal TMG helps meet that demand by delivering 1,000 mg of high-grade Trimethylglycine per serving. Plus, liposomal spheres derived from sunflower lecithin protect bioactive TMG during digestion and facilitate cellular membrane fusion, thereby enhancing absorbability and bioavailability.
Health Benefits
Health Benefits
Ingredients
Ingredients
Dosage
Dosage
Each capsule of Liposomal TMG provides you with clinically studied doses, in exactly the right combination, to give you an effective and safe amount with every dose.
Pure, Authentic, Natural Ingredients
GenuinePurity® Liposomal TMG Precision Methylation Support
At the core of your cellular machinery lies a biological process called methylation. A biochemical “on/off” switch, methylation is one of the body’s most essential regulatory mechanisms, influencing how our genes behave, cells communicate, and metabolic reactions proceed.
Trimethylglycine (TMG), or betaine, is a unique compound that naturally facilitates methylation. Known as the “master methyl donor” TMG provides the raw chemical units needed to transfer methyl groups, serving as a type of cellular “currency” that can help synthesize critical molecules, recycle nutrients, and maintain physiological balance.
Designed by a team of experts with 25+ years of experience, GenuinePurity® Liposomal TMG delivers a clinically studied 1,000 mg dose of purified Trimethylglycine in every serving. An advanced delivery system derived from sunflower lecithin acts like an “armored vehicle” shielding TMG from the hostile gastrointestinal tract, then biomimics endogenous structures to help foster cellular fusion and enhance bioavailability, supporting optimal results.
- Non-GMO
- Vegetarian Capsules
- Enhanced Bioavailability
- Scientifically Studied Dose
- No Unnecessary Additives
Healthy Homocysteine Metabolism
Homocysteine is an endogenous, sulfur-containing amino acid. Though not inherently harmful, homocysteine levels must remain within a relatively narrow range to support cardiovascular function.
Aging, poor diet, or a sedentary lifestyle could contribute to a homocysteine imbalance. High levels of homocysteine have been linked to increases in oxidative stress, vascular dysfunction, and reduced endothelial flexibility, placing strain on the cardiovascular system.
TMG serves as a substrate in the betaine-homocysteine methyltransferase (BHMT) pathway, naturally donating a methyl group to convert homocysteine into the essential amino acid methionine. In doing so, TMG supports normal cardiovascular function by promoting endothelial health and vascular physiology.
Sustaining the SAMe Cycle
The S-adenosylmethionine (SAMe) cycle, sometimes referred to as the methionine cycle, is the body’s natural metabolic “dispatcher” dispersing and distributing methyl groups to fuel healthy cellular behavior.
Gene expression, neurotransmitter production, creatine synthesis, hormone metabolism, cellular membrane construction, and cellular detoxification pathways depend on the SAMe cycle. Yet, aging, nutrient deficiencies, oxidative stress, and other factors can all dampen its efficiency.
TMG donates methyl groups to facilitate methionine regeneration (remethylation), a key biochemical process within the SAMe cycle. Through this action, TMG supports the supply chain required for continued SAMe cycling, enabling cellular stability, neurotransmitter synthesis pathways, and efficient metabolic processing.
Epigenetic Regulation
Our cells constantly adjust gene activity in response to physiological needs, environmental inputs, nutrient status, and metabolic conditions through a biochemical mechanism called epigenetic regulation.
A primary force behind this mechanism is DNA methylation, a biochemical process in which a methyl group attaches to specific regions of DNA, organically influencing whether a gene is more or less active. Proper DNA methylation is essential for normal cellular differentiation, adaptive stress responses, and tissue maintenance.
However, as we age, methylation patterns may be altered, leading to less stable cellular behavior, in a phenomenon researchers call “epigenetic drift”. By providing a continuous supply of methyl groups, TMG supports SAMe biosynthesis, thereby facilitating DNA methylation and epigenetic regulation.
Cognitive Biochemistry
The brain is one of the most metabolically demanding organs in the body. It relies on a tightly regulated network of biochemical reactions to maintain precise signaling, function, and structure.
Cognitive biochemistry, which depends on proper neurochemical balance, supports biopathways involved in mood modulation, learning and memory, stress adaptation, and neuronal resilience. To maintain favorable neurochemical conditions, the brain relies heavily on methylation.
SAMe-dependent methylation participates in biochemical reactions necessary for the synthesis of key neurotransmitters. In fact, SAMe methylation contributes to the production of dopamine, serotonin, and norepinephrine, central components of neuronal communication and overall cognitive balance.
Hepatic Fat Metabolism
The liver is a principal organ for lipid processing in the human body. Hepatic fat metabolism is pivotal for processing dietary fats, packaging them into lipoproteins, and regulating cholesterol balance.
When functioning normally, the liver serves as a site of biochemical transformation, continuously processing and transporting lipids through hepatic pathways, supporting metabolic wellness, cellular energy production, and overall physiological stability.
To transport fats effectively, the liver uses the structural phospholipid phosphatidylcholine to construct VLDL (very low-density lipoprotein) particles, which can be secreted from the liver. TMG facilitates phosphatidylcholine synthesis via methylation pathways, thereby fostering normal hepatic fat metabolism.
Cellular Osmoprotection
Our cells must maintain a delicate balance between fluids and dissolved particles to remain optimally efficient. This balance is crucial for enzymatic activity, nutrient transport, and mitochondrial function.
The body uses tiny molecules called osmolytes to maintain proper cellular balance. These biological “mediators” help preserve cellular stability, structural integrity, biochemical function, and metabolic efficiency, especially during physiological stress.
TMG acts as an organic osmolyte, capable of accumulating within cells to promote cellular hydration without disrupting protein function. This is particularly important in liver, kidney, muscle, brain, and intestinal epithelium cells, which are highly susceptible to osmotic stress.
GenuinePurity® Liposomal TMG The Bioavailability Breakthrough
Advanced Delivery System Bolsters Bioavailability
Standard TMG (Trimethylglycine) supplements are often degraded by the harsh conditions of the gastrointestinal tract, where they’re exposed to stomach acids and digestive enzymes, leading to inefficiency and waste.
That’s why we’ve engineered GenuinePurity® Liposomal TMG with an advanced liposomal delivery system designed based on contemporary scientific principles to support compound stability, absorbability, and bioavailability.
Derived from plant matter, this “stealth” delivery system mimics your cellular membranes, ferrying bioactive molecules through the stomach and into the bloodstream, where they can enter your cells, thereby maximizing uptake and achieving significant biological impact.
The GenuinePurity® Standard
GenuinePurity® Liposomal TMG is conceptualized, designed, and produced by our team of health supplement experts, who boast over a quarter-century of experience. All ingredients have been handpicked, tested, and assembled with one goal in mind—your health.
Like all GenuinePurity® supplements, our Liposomal TMG formula is manufactured in cGMP-certified facilities in the United States of America, where safety, consistency, and quality are held to the highest of standards.
We’re committed to providing you with precisely calibrated biological tools for deeper nourishment. Our scientifically backed formulas are built for those who demand the best. That’s why men and women around the globe rely on us for all their health supplement needs.
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