99% Pure Spermidine

A Clinically Proven Autophagy Activator

With Liposomal Encapsulation For Maximum Absorption & Effectiveness

  • Extend Lifespan Support
  • Cardiovascular Health
  • Enhance Metabolic Wellness
  • Promote Cognitive Function
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97-Day Money Back Guarantee

Each of our products offers 100% satisfaction and a 97-day money-back guarantee.

Pure, Authentic, Natural Ingredients

We combine ethical, natural ingredients with Liposomal Encapsulation Technology to guarantee optimal absorption and cellular effectiveness.

Made in the USA

GenuinePurity® products are proudly made inside cGMP-certified production facilities in the United States of America.

100% Naturally Sourced Spermidine

Beware of synthetic spermidine products. These cheap imitations have ONLY been tested on mice, not humans. Unlike our 100% naturally-sourced spermidine from wheat germ extract – which has been used for thousands of years by humans with tremendous success.

Extend Lifespan
Support Cardiovascular Health
Enhance Metabolic Wellness
Promote Cognitive Function

How to use:
Take 2 capsules per day, preferably with food. (Or as directed by a health professional.)

Certificates of Analysis

We live in a world where many supplement companies say their formulas contain certain ingredients when in reality they don’t.

Our products are tested and certified by third party laboratories. Always be sure to see a Certificate of Analysis (COA) before purchasing any supplement, from us or anyone else, for that matter.

Health Benefits

Prevent the accumulation of senescent cells known for age-related diseases. Our Spermidine supplement also supports the following:

Blood Vessel Function
Enhances vascular function by possibly maintaining the flexibility and dilation of blood vessels.

Insulin Sensitivity
Enhances metabolic wellness by potentially improving insulin sensitivity. Insulin is an essential hormone for controlling blood sugar levels.

Neurogenesis
Some studies suggest spermidine promotes neurogenesis–the process of generating new neurons in the brain.

Inflammation Prevention
Autophagy helps remove damaged cellular components and combat inflammation by eliminating sources of inflammation within cells.

Ingredients

Key Ingredients
Spermidine (from Wheat Germ Extract)

Other Ingredients
Vegetable Cellulose (Capsule), Microcrystalline Cellulose, Phospholipid Complex (Sunflower Lecithin, Phosphatidylcholine), Silicon Dioxide, Vegetable Stearate.

Dosage

Each capsule of Liposomal Spermidine provides you with clinically studied doses, in exactly the right combination, to give you an effective and safe amount with every dose.

  • 99% Pure Spermidine - 8mg

Please note that we have recently redesigned the packaging for Liposomal Spermidine. Until all old inventory sells through, we are unable to guarantee which version of the packaging you receive, but the product is identical.

GenuinePurity Spermidine - Supplement Facts

Get A Powerful Dose of 8 mg

Check the label: Many spermidine products ONLY offer a pitifully small dose of 1mg… 3mg… or 5mg of spermidine. But with GenuinePurity® Spermidine, you get a powerful daily dose of 8 mg. This recommended dose is safe without any negative reported side-effects.

Enhanced Bioavailability With Liposomal Encapsulation For Better Results

Our revolutionary spermidine formula is made using liposomal encapsulation technology that helps increase the effectiveness in three distinct ways:

  • #1

    Forms a safeguarding “shield,” protecting the Spermidine from stomach acids and preserving the integrity

  • #2

    Amplifies solubility, simplifying the absorption process for the Spermidine to enter your bloodstream effortlessly

  • #3

    Elevates cellular uptake by facilitating liposomal fusion with cell membranes, ensuring the Spermidine is delivered directly to your cells

Blood Vessel Function - GenuinePurity Spermidine

Made from Spermidine -Rich Wheat Germ

“Wheat germ was reported as one of the natural sources of high polyamine, especially spermidine.” Food Science & Nutrition Volume 11, Issue 11 2023

Wheat germ is the nutrient-rich embryo of the wheat kernel, containing a concentrated source of vitamins, minerals, and essential nutrients. It is a natural source of spermidine, a polyamine that has been linked to amazing longevity benefits. Researchers believe spermidine in wheat germ induces processes like autophagy, enhances cellular health, and contributes to anti-aging effects, making it a valuable component for overall well-being.

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Get Free Shipping Within The Continental USA

GenuinePurity Spermidine

3rd Party Tested For Your Safety & Peace of Mind

Our formula is 3rd party tested so you KNOW you’re getting the “real” deal. Which is more important now than ever before. Because now with the incredible anti-aging benefits of spermidine becoming more well-known, “fake” spermidine products are flooding the market without any proof of authenticity.

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Spermidine Extends Lifespan

“Health- and life-span–promoting effects are documented for dietary or otherwise externally supplied spermidine”- Science Journal 2018
“…supplementation of spermidine extends lifespan and health span across species” - Autophagy Journal 2019
“External supply of the natural polyamine spermidine can extend life span” - Impact Journals: Aging 2018
Blood Vessel Function - GenuinePurity Spermidine

Autophagy stimulation

Autophagy is a cellular process that involves the recycling of damaged or malfunctioning cellular components. Spermidine has been shown to induce autophagy, which may help cells remove dysfunctional elements and maintain cellular health.

Anti-inflammatory effects

Long-term inflammation is associated with aging and age-related health issues. Spermidine has been suggested to support healthy anti-inflammatory function, which may contribute to overall health and longevity.

GenuinePurity Spermidine
GenuinePurity Spermidine

Mitochondrial function

Spermidine has been linked to improved mitochondrial function. Mitochondria are the energy-producing organelles in cells, and their proper function is crucial for overall cellular health.

Improves Cardiovascular Functions

“Spermidine has beneficial effects on health and lifespan in mice, and that these effects are the result of improved cardiovascular function”- Nat Med 2016
“Spermidine-fed rats manifested delayed onset of hypertension, attenuated cardiac hypertrophy, and improved diastolic function” American Heart Association Journals 2017
“New research has now found that spermidine, a dietary polyamine, promotes long life and exerts a cardioprotective effect in mice.” - Impact Journals: Aging 2018
Blood Vessel Function - GenuinePurity Spermidine

Blood Vessel Function

Spermidine has been studied for its potential to improve blood vessel function. It may help in maintaining the flexibility and dilation of blood vessels, which is important for normal blood flow and blood pressure regulation.

Reduces Inflammation

Long-term inflammation is a contributing factor to cardiovascular problems. Spermidine has been investigated for its inflammation-reducing properties which may play a role in supporting the cardiovascular system.

GenuinePurity Spermidine
GenuinePurity Spermidine

Antioxidant Properties

Spermidine has antioxidant effects, meaning it can help neutralize harmful free radicals in the body. Excessive free radicals can contribute to oxidative stress, which is associated with cardiovascular problems. By reducing oxidative stress, spermidine may help maintain a healthy heart.

Amplify your health and lifespan with Spermidine

Enhances Metabolic Health

“Evidence from in vitro and in vivo studies consistently showed that increased spermidine and polyamine catabolism had beneficial effects on metabolic pathways” - Science Direct 2021
Spermidine is a biogenic polyamine that plays a crucial role in mammalian metabolism.” - Journal Nutrients 2023
“In 2018, two animal studies consistently showed that spermidine supplementation caused a significant loss of weight and improved insulin resistance in high-fat diet-induced obese mice” - Journal Nutrients 2022
Autophagy andCellular Health - GenuinePurity Spermidine

Autophagy and Cellular Health

Spermidine has been shown to induce autophagy, a cellular process that involves the degradation and recycling of damaged or dysfunctional cellular components. This process is crucial for maintaining cellular health and could play a role in overall metabolic function.

Insulin Sensitivity

Some studies have suggested that spermidine may influence insulin sensitivity. Improved insulin sensitivity is associated with better glucose metabolism and reduced risk of insulin resistance, which is a key factor in metabolic well-being.

blood glucose monitor - GenuinePurity Spermidine
AMPK Activation - GenuinePurity Spermidine

AMPK Activation

Adenosine monophosphate-activated protein kinase (AMPK) is an enzyme that plays a crucial role in cellular energy balance. Some research has indicated that spermidine may activate AMPK, which could have downstream effects on metabolism, including enhanced glucose uptake and fatty acid oxidation.

Supports & Preserves Cognitive Functions

“The maintenance of mitochondrial and autophagic function is essential for enhanced cognition by spermidine” - CellPress
“[Spermidine] is involved in preserving mitochondria and cognitive function” - Frontiers Journal 2022
GenuinePurity Fisetin - Physical injury is a common inflammatory Mediator

Autophagy Induction

Spermidine has been shown to induce autophagy, a cellular process that involves the removal of damaged or dysfunctional cellular components. This process is crucial for maintaining the health of neurons and may contribute to overall cognitive function.

Neurogenesis

Some studies have suggested that spermidine may promote neurogenesis, which is the process of generating new neurons in the brain. This could be particularly relevant for cognitive function and maintaining brain health.

GenuinePurity Fisetin - NF-kB Structure
Neurological Health - GenuinePurity Fisetin

Support for Neurological Health

Preliminary research has explored the potential of spermidine in maintaining proper neurological function. Neurodegenerative issues come with age, and often involve the accumulation of misfolded proteins and oxidative stress. Spermidine’s ability to induce autophagy and reduce oxidative stress may contribute to preserving neurological health.

Reduces Inflammation & Oxidation

“Spermidine, a natural polyamine, has been reported to regulate inflammation through inducing anti-inflammatory (M2) macrophages” Science Direct 2020
“Spermidine is a naturally occurring polyamine compound that has recently emerged with anti-aging properties and suppresses inflammation and oxidation.” - Biomolecules & Therapeutics 2018
GenuinePurity Liposomal Fisetin

Inhibition of Inflammatory Mediators

Spermidine may modulate the production of inflammatory mediators, such as cytokines and chemokines. These molecules play a key role in the inflammatory response, and the regulation of their production by spermidine could contribute to proper anti-inflammatory function.

Suppression of Inflammatory Signaling Pathways

Spermidine has been suggested to interfere with specific signaling pathways associated with inflammation. For example, it may impact nuclear factor-kappa B (NF-κB), a transcription factor that plays a central role in the regulation of immune and inflammatory responses.

Immune Response - GenuinePurity Liposomal Fisetin
Anti-Inflammatory Effects - GenuinePurity Liposomal Fisetin

Autophagy-Related Anti-Inflammatory Effects

The induction of autophagy by spermidine could indirectly contribute to its potential to provide anti-inflammatory support. Autophagy helps remove damaged cellular components and combat inflammation by eliminating sources of inflammation within cells.

Spermidine Declines with Age

“The concentration of spermidine declines with age” - Aging and Disease Journal

New research shows spermidine levels begin declining between ages 35 and 40. And once this descent begins, the decline of spermidine speeds-up with age. This of course causes an accelerated aging effect, along with a myriad of potential health complications.

Graph: Spermidine levels in your cells decline after age of 35.
GenuinePurity Liposomal Fisetin

Spermidine Increases Longevity By Inducing Autophagy

“[Spermidine] is a well-known autophagy inducer” - Neuropeptides, Volume 83, October 2020

Spermidine induces autophagy, a cellular process that facilitates the degradation and removal of damaged or malfunctioning cellular components. By promoting autophagy, spermidine helps cells maintain their health and functionality by recycling and eliminating unnecessary or poorly functioning structures. This process is crucial for cellular maintenance, and its stimulation by spermidine may contribute to overall well-being and potential longevity.

Amplify your health and lifespan with Spermidine

GenuinePurity Liposomal Fisetin is made in cGMP-Certified Facilities

GenuinePurity® Spermidine Is Made In cGMP-Certified Facilities

Each bottle of GenuinePurity® Spermidine is made in the USA in cGMP-certified facilities for consistent quality and purity. We follow the highest manufacturing standards so you can feel certain you’re getting the best spermidine in its purest, most potent form.

GenuinePurity Fisetin - 97 Days Money Back Guarantee

Try It RISK-FREE For 97 Days

Our promise to you is simple: If, for any reason, you are not 100% satisfied, simply return the two empty containers within 97 days from the time of delivery for a full refund excluding shipping charges. If you wish to take advantage of the price discount by ordering multiple containers, don’t worry! Any unopened containers returned along with your opened containers within the 90-day money-back guarantee period will also be eligible for a full refund less any shipping charges. That said, we must respectfully remind you not to ship back any product after the 90-day refund period has expired. Returns must be received back at the warehouse within 97 days of delivery with no exceptions. Please note that we must limit refunds to one order per customer.

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Get Free Shipping Within The Continental USA

GenuinePurity Liposomal Fisetin

FAQs

No matter what your question is, our team is always here to help with prompt and accurate answers.

What are the ingredients?

99% Pure Spermidine (from Wheat Germ Extract).

How much Spermidine is in every dose?

A daily recommended dose of 8mg of Spermidine.

What are the directions?

2 capsules daily, preferably with meals.

What are the details of the money-back guarantee?

Our guarantee to you is simple: You either love our formula or your money back. In fact, you can “test drive” Genuine Purity™ Spermidine with our incredible 90-day, money-back guarantee.

Here’s how it works: Place your order today. When you do, you’ll have 90 days to decide whether our formula is right for you. If you’re unsatisfied, for any reason, simply return the bottles within 90 days for a full refund of the purchase price.

Give it a try today!

How do I order?

Ordering is fast, easy and secure. You’ll land on our 100% secure order page where you can quickly fill in your billing and shipping information.

Simply click here to get started.

Scientifically-Led, Purposely-Developed

At GenuinePurity®, we believe that a life of quality transcends quantity. 

Our supplements are developed with ethically sourced ingredients and made in the USA in FDA-inspected, cGMP-certified facilities, ensuring the most reliable support for a healthier future.